Method development and optimization
Janusz Pawliszyn
,
University of Waterloo
,
Canada
Level
Basic
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Interview Janusz Pawliszyn
SPME in perspective
Principles of SPME
Experimental parameters affecting extraction efficiency
Interfacing and automating
Method development and optimization
> Selection of coating
> Selection of extraction mode
> Selection of agitation technique
> Sample volume optimization
> Extraction time optimization
> Extraction conditions optimization
> Selection of separation and/or detection technique
Optimization of desorption conditions
Selection of the calibration method
Method evaluation
References
Food and fragrance studies involving SPME
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